superscan bone scan
While a superscan is relatively uncommon its recognition is important as it is associated with a number of important underlying diseases. A superscan is an imaging appearance on a Tc-99m diphosphonate bone scan which occurs as a result of a high ratio of bone to soft tissue tracer accumulation.
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Love et al 2003.
. Pathology Etiology This appearance can result from a range of causes. It is usually accompanied by absent or faint renal activity Sy et al 1975. A bone scan in which there is excessive skeletal radioisotope uptake in relation to soft tissues along with absent or faint activity in the genitourinary tract is known as a superscan.
Submitted by Dr Rishu Sangal Consultant. A metastatic superscan tends to have uptake throughout the axial skeleton and proximal appendicular skeleton often somewhat heterogeneous. Prostate cancer 4680 was the most common cause of superscan appearance followed by breast cancer 1080.
He subsequently had a scrotal orchidectomy and received 30Gy of external beam radiation to the pelvis for intractable bone pain. Die Skelettszintigrafie auch Knochenszintigrafie engl. Total of 6027 bone scans were examined in a 5-year period and out of which 80 cases were diagnosed as superscan.
171 Technique A 20 mCi dose of 99m Tc-MDP is administered intravenously. Metabolic superscan MSS was noted in 90 of the Graves cases 20 in TNG and in none of the AT group. Bereiche mit einem erhöhten Knochenstoffwechsel Herde finden sich beispielsweise bei Knochenmetastasen.
Although a superscan can occur in a broad range of conditions both malignant and metabolic the vast majority are due to high volume bony. A superscan is defined as bone scan planar imaging with diffuse increased skeletal tracer uptake relative to soft tissue combined with diminished or non-existent renal activity Brenner et al 2012. 19042022 Interesting image Technetium 99m PSMA Superscan Mimicking a Bone Scan Gone Wrong.
In contrast a metabolic superscan tends to be more uniform and involve both the axial and more peripheral skeleton including the distal extremities calvarium and mandible. Bone scan is part of the staging modality commonly used to evaluate bone metastasis. A bone scan with diffused increased skeletal tracer uptake relative to soft tissue combined with faint renal activity is known as a superscan.
However a primary concern are false negatives associated with bone scans where diffuse metastasis is indistinguishable on superscans. Intense osteoblastic activity in the bones causes diminished renal and background soft tissue uptake. Out of 6027 patients referred for bone scan 307 patients.
In todays modern healthcare system bone scans are relatively quick inexpensive and widely available. There were no significant differences regarding Ca AP and PTH between the Graves and non-Graves groups p 005. Monday June 04 2012 bone scan skeletal metastasis superscan.
In bone imaging the term superscan has been used to describe the appearance of high skeletal uptake of radionuclide combined with low background activity Osmond etal 1975. 1 2 3 4 and 5 Full size image Fig. The addition of the bone.
Disturbances in bone metabolism are more prevalent in Graves disease than in other types of hyperthyroidism. This is a report of bone scintigraphy demonstrating superimposed metastatic and metabolic superscan in a patient with prostate cancer who subsequently developed renal osteodystrophy. Two years after the first.
A superscan is defined as a bone scan which demonstrates markedly increased skeletal radioisotope uptake relative to soft tissues in association with absent or faint genito-urinary tract activity. Breast cardiac MRCP angiogram head spine shoulder elbow wrist hip knee and ankle. This appearance has been associated with two main pathological groups.
The overall incidence of superscan in different type of cancers was 13 806027. Bone scan genannt ist ein nuklearmedizinisches bildgebendes Verfahren Szintigrafie das zum Nachweis von Knochen-Anteilen mit einem erhöhten Knochenstoffwechsel dient. BONE Imaging by CT andor MRI Include chest CT1 Include prostate MRI if necessary2 Imaging frequency.
A superscan is a term given to the appearances on a nuclear bone scan when bony uptake of Tc99m disphosponate is so profound that the usual physiological uptake observed in the kidneys is no longer apparent. NON-METASTATIC CASTRATE RESISTANT PROSTATE CANCER NMCRPC LYMPH NODES Perform lesion. Assess soft tissue lung liver adrenal CNS lesions per RECIST 11.
It may occur in widespread metastatic. Superscans on bone scintigraphy have been described mostly in metastatic and metabolic bone diseases with different patterns and appearances of radiotracer uptake. Every 89 weeks for the first 6 months then every 12 weeks.
Superscan offers the following services to patients. A super scan in scintigraphy is defined as intense symmetric radiotracer activity in the bones increased bone. 17 superscan Prostate Cancer CASE 17 Clinical Presentation A 72-year-old man with a history of metastatic prostate cancer is referred for a bone scan because of pain in the left shoulder and lower neck Fig.
Soft tissue uptake ratio and diminished renal parenchymal activity 1. This bone scan of a patient with metastatic disease demonstrates the superscan phenomenon. Tracer uptake is so avid in bone that there is almost no renal excretion the kidneys are barely visualised.
The bone scan images show skeletal involvement of the skull ribs spine and pelvis. Apart from prostate cancer which is the most common condition associated with a superscan other malignancies like breast cancer lung cancer 1 2 3 4 can cause superscan appearance on.
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